| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MprB | cckA | CLOSCI_03930 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.510 |
| MprB | walR_5 | CLOSCI_03930 | CLOSCI_01764 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.1e-51 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.696 |
| WalK_3 | cckA | CLOSCI_01763 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2500 3.6e-47 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.494 |
| WalK_3 | comEA | CLOSCI_01763 | CLOSCI_01765 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2500 3.6e-47 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: CytoplasmicMembrane, score: 9.49. | 0.683 |
| WalK_3 | walR_5 | CLOSCI_01763 | CLOSCI_01764 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2500 3.6e-47 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.1e-51 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.926 |
| WalK_4 | cckA | CLOSCI_03389 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.529 |
| WalK_4 | phoR_5 | CLOSCI_03389 | CLOSCI_03395 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.618 |
| WalK_4 | walR_5 | CLOSCI_03389 | CLOSCI_01764 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.1e-51 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.755 |
| cckA | MprB | CLOSCI_02760 | CLOSCI_03930 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.510 |
| cckA | WalK_3 | CLOSCI_02760 | CLOSCI_01763 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2500 3.6e-47 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.494 |
| cckA | WalK_4 | CLOSCI_02760 | CLOSCI_03389 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.529 |
| cckA | phoR_2 | CLOSCI_02760 | CLOSCI_03175 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 1.3e-58 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.647 |
| cckA | phoR_5 | CLOSCI_02760 | CLOSCI_03395 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.811 |
| cckA | resE_4 | CLOSCI_02760 | CLOSCI_00965 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btk:BT9727_4401 2.7e-90 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.82. | 0.483 |
| cckA | resE_6 | CLOSCI_02760 | CLOSCI_04029 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 2.0e-62 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase. | 0.706 |
| cckA | walR_5 | CLOSCI_02760 | CLOSCI_01764 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.1e-51 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.746 |
| cckA | zraS_2 | CLOSCI_02760 | CLOSCI_02829 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecp:ECP_4216 4.8e-30 sensor protein ZraS K07709; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.515 |
| comEA | WalK_3 | CLOSCI_01765 | CLOSCI_01763 | COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2500 3.6e-47 phoR; two-component sensor histidine kinase K07636; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.683 |
| comEA | walR_5 | CLOSCI_01765 | CLOSCI_01764 | COG: COG1555 DNA uptake protein and related DNA-binding proteins; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.1e-51 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.749 |
| phoR_2 | cckA | CLOSCI_03175 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 1.3e-58 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.647 |