STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
argDAminotransferase, acetylornithine/succinylornithine family; KEGG: cje:Cj0227 5.6e-106 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (391 aa)    
Predicted Functional Partners:
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
 
 0.999
argJ
Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.998
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.994
argG
KEGG: chy:CHY_2260 4.7e-134 argG; argininosuccinate synthase K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.937
argH
Argininosuccinate lyase; KEGG: cpe:CPE0690 2.3e-139 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.921
YpeA
Acetyltransferase, GNAT family; KEGG: rba:RB7615 1.0e-10 putative acetyltransferase K00680; COG: COG0456 Acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.826
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 0.814
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.744
ygeW
Putative carbamoyltransferase YgeW; KEGG: mta:Moth_1996 4.8e-45 ornithine carbamoyltransferase K00611; COG: COG0078 Ornithine carbamoyltransferase; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
  
 0.729
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 
 0.720
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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