Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS07135.1Hypothetical protein; Psort location: Extracellular, score: 8.82. (43 aa)    
Predicted Functional Partners:
HemE_5
KEGG: swo:Swol_0417 7.7e-54 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
       0.568
EDS07137.1
Hypothetical protein; KEGG: swo:Swol_0417 0.0058 uroporphyrinogen decarboxylase K01599; Psort location: Cytoplasmic, score: 8.87.
       0.568
metI
ABC transporter, permease protein; KEGG: baa:BA_0884 1.5e-41 binding-protein-dependent transport systems inner membrane component K00294; COG: COG2011 ABC-type metal ion transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
       0.568
metN
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
       0.568
metQ
NLPA lipoprotein; COG: COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.
       0.568
EDS07141.1
Hypothetical protein; KEGG: mmr:Mmar10_0193 4.0e-08 ATP-dependent metalloprotease FtsH; COG: COG0465 ATP-dependent Zn proteases; Belongs to the AAA ATPase family.
       0.473
GrdE_1
Putative betaine reductase complex component B subunit alpha; KEGG: tte:TTE1879 3.2e-64 GrdE proprotein; COG: NOG06476 non supervised orthologous group.
       0.405
EDS07143.1
KEGG: chy:CHY_2393 4.0e-13 grdB; glycine reductase, selenoprotein B; COG: NOG11573 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.405
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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