Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
cpdA_2Putative phosphoesterase; COG: COG1409 Predicted phosphohydrolases; Psort location: Cytoplasmic, score: 8.87. (266 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.957
recF_3
Hypothetical protein; KEGG: fnu:FN0522 0.0021 exonuclease SBCC K03546; COG: COG4717 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 7.80.
  
 0.887
sbcC
KEGG: ctc:CTC00579 8.6e-110 sbcC; exonuclease sbcC K03546; COG: COG0419 ATPase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87.
  
 0.887
appA_4
ABC transporter, substrate-binding protein, family 5; KEGG: shn:Shewana3_2650 1.7e-35 acetate kinase K00925; COG: COG0747 ABC-type dipeptide transport system, periplasmic component; Psort location: Cellwall, score: 9.18.
 
     0.780
recQ
KEGG: cpf:CPF_0327 4.3e-140 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
  
 0.777
OppF_4
KEGG: reh:H16_B0716 5.5e-76 dppF3; ABC-type transporter, ATPase component: PepT family; COG: COG4608 ABC-type oligopeptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
       0.773
oppD_4
KEGG: reh:H16_A1303 4.9e-68 ABC-type transporter, ATPase component: PepT family; COG: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
       0.773
gsiD
KEGG: rha:RHA1_ro08170 0.00013 ABC transporter, permease component; COG: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: CytoplasmicMembrane, score: 10.00.
       0.732
DppB_4
KEGG: rha:RHA1_ro09047 1.7e-58 ABC peptide transporter, permease component K02033; COG: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; Psort location: CytoplasmicMembrane, score: 10.00.
       0.732
rbn_2
Metallo-beta-lactamase domain protein; KEGG: sph:MGAS10270_Spy0181 1.5e-34 metal-dependent hydrolase; COG: COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; Psort location: Cytoplasmic, score: 8.87.
 
     0.707
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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