Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SenX3ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 3.6e-33 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (163 aa)    
Predicted Functional Partners:
sphR_1
Response regulator receiver domain protein; KEGG: ava:Ava_3369 3.9e-27 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.939
EDS06966.1
ABC transporter, ATP-binding protein; KEGG: fal:FRAAL2864 3.5e-49 putative transport protein of outer membrane lipoproteins (ABC superfamily, atp_bind) (partial match); COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.82.
 
     0.800
EDS06965.1
Efflux ABC transporter, permease protein; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.75.
 
   
 0.706
phoR_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
   0.665
EDS07005.1
Hypothetical protein; KEGG: rru:Rru_A3651 0.00023 ABC transporter component K06020; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: Extracellular, score: 8.82.
 
     0.628
EDS07002.1
Hypothetical protein; KEGG: cch:Cag_0337 0.0018 ATPase K06020; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.75.
 
   
 0.619
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 
 0.576
cseB
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.3e-37 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.573
regX3_4
Response regulator receiver domain protein; KEGG: ava:Ava_3369 3.7e-38 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.561
phoP_4
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.560
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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