close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mta_4Transcriptional regulator, MerR family; KEGG: syn:sll0794 3.8e-06 corR, merR, cobH, cbiC; cobalt-dependent transcriptional regulator (MerR (mercuric resistance operon regulatory protein)-like domain in N-terminal half), precorrin isomerase, Precorrin-8X methylmutase (in C-terminal half) K01833; COG: COG0789 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87. (280 aa)    
Predicted Functional Partners:
EDS06999.1
Hypothetical protein; COG: COG0582 Integrase; Psort location: Cytoplasmic, score: 8.87; Belongs to the 'phage' integrase family.
 
     0.514
EDS05182.1
Pentapeptide repeat protein; COG: COG1357 Uncharacterized low-complexity proteins.
  
     0.445
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.443
dnaJ_1
Putative chaperone protein DnaJ; KEGG: cme:CMJ043C 5.2e-07 phycocyanobilin lyase alpha subunit K02288; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65.
  
 
 0.440
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.440
dnaJ_3
DnaJ domain protein; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.440
dnaJ_2
DnaJ domain protein; KEGG: cya:CYA_0373 0.00021 serine/threonine protein kinase K00924; COG: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; Psort location: Cytoplasmic, score: 9.65.
  
 
 0.440
glnA-2
KEGG: chy:CHY_0704 5.3e-158 glnA1; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.439
zntR_1
Transcriptional regulator, MerR family; KEGG: eci:UTI89_C3737 3.2e-07 yhdM; Zn(II)-responsive regulator of ZntA; COG: NOG23448 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.406
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (28%) [HD]