Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDS06941.1Oxidoreductase; COG: NOG39254 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (162 aa)    
Predicted Functional Partners:
EDS06964.1
C4-dicarboxylate transporter/malic acid transport protein; COG: COG1275 Tellurite resistance protein and related permeases; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.738
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.618
EDS06942.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.511
EDS06943.1
Hypothetical protein; COG: COG3655 Predicted transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
       0.498
EDS06944.1
Hypothetical protein; KEGG: efa:EF2060 0.0083 cydB; cytochrome d ubiquinol oxidase, subunit II K00426; COG: NOG16658 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
       0.498
fumB
Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; KEGG: chy:CHY_1374 5.7e-58 fumarate hydratase, beta subunit K01678; COG: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
      0.480
plsC_1
Acyltransferase; KEGG: oih:OB0869 3.4e-28 1-acyl-sn-glycerol-3-phosphate acetyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.438
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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