Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
recF_3Hypothetical protein; KEGG: fnu:FN0522 0.0021 exonuclease SBCC K03546; COG: COG4717 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 7.80. (515 aa)    
Predicted Functional Partners:
yhaO
Ser/Thr phosphatase family protein; KEGG: gox:GOX1019 3.8e-06 putative exonuclease K01146; COG: COG0420 DNA repair exonuclease; Psort location: Cytoplasmic, score: 8.87.
 
 0.994
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.934
recQ
KEGG: cpf:CPF_0327 4.3e-140 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
  
 0.907
cpdA_2
Putative phosphoesterase; COG: COG1409 Predicted phosphohydrolases; Psort location: Cytoplasmic, score: 8.87.
  
 0.887
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.887
resE_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK4604 5.0e-50 vanS; sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36.
 
     0.802
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.776
saeR
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 2.0e-39 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
       0.757
EDS07735.1
DEAD2 domain protein; KEGG: mja:MJ0942 7.3e-20 dinG; ATP-dependent DNA helicase DinG, putative K01529; COG: COG1199 Rad3-related DNA helicases; Psort location: Cytoplasmic, score: 8.87.
   
 0.711
EDS05874.1
Hypothetical protein; COG: NOG13188 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
    
 0.704
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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