Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgcAPhosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cac:CAC2337 6.6e-167 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87. (577 aa)    
Predicted Functional Partners:
pgi
KEGG: bcl:ABC2906 1.4e-164 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
 
 
 0.964
glgD
Glucose-1-phosphate adenylyltransferase, GlgD subunit; KEGG: tma:TM0239 5.7e-81 glucose-1-phosphate adenylyltransferase K00975; COG: COG0448 ADP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
 
 0.959
glcK
ROK family protein; KEGG: cac:CAC2613 3.9e-91 glcK; transcriptional regulators of NagC/XylR family K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.938
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.935
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
 
 0.932
glgP
Phosphorylase, glycogen/starch/alpha-glucan family; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.927
glgP-2
Phosphorylase, glycogen/starch/alpha-glucan family; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.927
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
 0.925
rbsK-3
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.923
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.923
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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