Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
tktATransketolase, thiamine diphosphate binding domain protein; KEGG: cpe:CPE0296 8.5e-87 tktN; transketolase N-terminal section K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score: 8.87. (278 aa)    
Predicted Functional Partners:
dxs_1
Transketolase, C-terminal domain protein; KEGG: lmo:lmo1033 1.8e-86 similar to transketolase K00615; COG: COG3958 Transketolase, C-terminal subunit.
 0.999
dxs_2
KEGG: rha:RHA1_ro00814 3.5e-58 possible transketolase, C-terminal subunit K00615; COG: COG3958 Transketolase, C-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
 0.999
dxs_3
Transketolase, pyridine binding domain protein; KEGG: cno:NT01CX_1268 1.3e-97 transketolase, C-terminal subunit K00615; COG: COG3958 Transketolase, C-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
 0.999
rpe
KEGG: cno:NT01CX_2237 3.6e-56 ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score: 8.87.
  
 0.987
fsa
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.968
fas2
Transketolase, thiamine diphosphate binding domain protein; KEGG: mta:Moth_0236 1.5e-48 transketolase-like K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.916
Tkt_1
Transketolase, thiamine diphosphate binding domain protein; KEGG: lmf:LMOf2365_1053 7.1e-83 transketolase, N-terminal subunit K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 
0.906
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 
0.904
gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: chu:CHU_2987 1.5e-96 gapA; glyceraldehyde-3-phosphate dehydrogenase A K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.98.
    
  0.903
gap-2
KEGG: fth:FTH_1121 1.5e-121 gapA; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.98.
    
  0.903
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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