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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
blaRRegulatory protein blaR1; KEGG: bsu:BG11507 5.4e-37 ybxI, ybdS; similar to beta-lactamase K01467; COG: COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component; Psort location: CytoplasmicMembrane, score: 9.99. (568 aa)    
Predicted Functional Partners:
blaI
Transcriptional regulator, BlaI/MecI/CopY family; KEGG: bcz:BCZK0993 2.2e-24 blaI; beta-lactamase (penicillinase) repressor K01467; COG: COG3682 Predicted transcriptional regulator.
 
 
 0.997
EDS06846.1
Hypothetical protein.
  
    0.544
EDS08761.1
ABC-2 type transporter; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.425
EDS08576.1
Hypothetical protein; KEGG: cpf:CPF_1123 1.3e-16 cell wall-associated serine proteinase K01361; COG: NOG17334 non supervised orthologous group.
  
     0.417
pbp
Penicillin-binding protein, transpeptidase domain protein; KEGG: ser:SERP2521 3.7e-102 mecA; penicillin-binding protein 2' K02545; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.83.
 
   
 0.415
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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