Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (302 aa)    
Predicted Functional Partners:
EDS06525.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.849
tsaD
Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
    0.752
yeaZ
Universal bacterial protein YeaZ; KEGG: ctc:CTC02444 6.5e-41 O-sialoglycoprotein endopeptidase K01409; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Cytoplasmic, score: 8.87.
 
     0.696
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
   
   0.655
rimI
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
       0.641
tsaE
Hydrolase, P-loop family; KEGG: cjk:jk1734 6.8e-13 alr; hypothetical protein K01775; COG: COG0802 Predicted ATPase or kinase; Psort location: Cytoplasmic, score: 8.87.
       0.641
EDS06530.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
       0.548
ltaE
Beta-eliminating lyase; KEGG: cac:CAC3420 6.2e-116 low specificity L-threonine aldolase K01620; COG: COG2008 Threonine aldolase; Psort location: Cytoplasmic, score: 8.87.
       0.528
mecB
COG: COG4862 Negative regulator of genetic competence, sporulation and motility; Psort location: Cytoplasmic, score: 8.87.
 
     0.480
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
   
 0.477
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.