| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS06380.1 | dnaN | CLOSCI_02497 | CLOSCI_01935 | DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.532 |
| EDS06380.1 | mutL | CLOSCI_02497 | CLOSCI_00527 | DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.521 |
| EDS06380.1 | mutY | CLOSCI_02497 | CLOSCI_02157 | DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.417 |
| EDS06380.1 | polA | CLOSCI_02497 | CLOSCI_00644 | DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.980 |
| EDS06544.1 | EDS06545.1 | CLOSCI_02158 | CLOSCI_02159 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG17660 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.475 |
| EDS06544.1 | mutY | CLOSCI_02158 | CLOSCI_02157 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.773 |
| EDS06545.1 | EDS06544.1 | CLOSCI_02159 | CLOSCI_02158 | Hypothetical protein; COG: NOG17660 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 0.475 |
| EDS06545.1 | mutY | CLOSCI_02159 | CLOSCI_02157 | Hypothetical protein; COG: NOG17660 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.475 |
| EDS06671.1 | mutY | CLOSCI_02286 | CLOSCI_02157 | Hypothetical protein; KEGG: reh:H16_A2653 1.6e-14 G:T/U mismatch-specific DNA glycosylase K01249; COG: COG3663 G:T/U mismatch-specific DNA glycosylase; Psort location: Cytoplasmic, score: 8.87. | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.814 |
| EDS06671.1 | xth | CLOSCI_02286 | CLOSCI_01649 | Hypothetical protein; KEGG: reh:H16_A2653 1.6e-14 G:T/U mismatch-specific DNA glycosylase K01249; COG: COG3663 G:T/U mismatch-specific DNA glycosylase; Psort location: Cytoplasmic, score: 8.87. | Exodeoxyribonuclease III; KEGG: cac:CAC0222 4.4e-106 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score: 9.98. | 0.845 |
| birA | mutY | CLOSCI_00957 | CLOSCI_02157 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.471 |
| birA | xth | CLOSCI_00957 | CLOSCI_01649 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Exodeoxyribonuclease III; KEGG: cac:CAC0222 4.4e-106 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score: 9.98. | 0.839 |
| dnaN | EDS06380.1 | CLOSCI_01935 | CLOSCI_02497 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.532 |
| dnaN | mutL | CLOSCI_01935 | CLOSCI_00527 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.927 |
| dnaN | mutY | CLOSCI_01935 | CLOSCI_02157 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.494 |
| dnaN | polA | CLOSCI_01935 | CLOSCI_00644 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.991 |
| dnaN | xth | CLOSCI_01935 | CLOSCI_01649 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; KEGG: cac:CAC0222 4.4e-106 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score: 9.98. | 0.915 |
| mutL | EDS06380.1 | CLOSCI_00527 | CLOSCI_02497 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.521 |
| mutL | dnaN | CLOSCI_00527 | CLOSCI_01935 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.927 |
| mutL | mutY | CLOSCI_00527 | CLOSCI_02157 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family. | 0.408 |
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