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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS06545.1Hypothetical protein; COG: NOG17660 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (290 aa)    
Predicted Functional Partners:
EDS05027.1
Stage II sporulation protein E; KEGG: mta:Moth_0103 3.8e-08 serine phosphatase K06382; COG: NOG28446 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
    0.669
mepM_1
KEGG: cya:CYA_1627 1.7e-20 peptidase, M23B family; COG: COG0739 Membrane proteins related to metalloendopeptidases.
  
  
 0.632
EDS05611.1
Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.557
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.540
topB_2
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
   
 
 0.540
EDS07477.1
HD domain protein; KEGG: ava:Ava_1777 4.6e-26 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
  
    0.515
EDS08345.1
Lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; COG: NOG17940 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.513
EDS05417.1
Hypothetical protein; KEGG: shn:Shewana3_3829 0.0029 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
  
    0.485
mutY
KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family.
       0.475
EDS06544.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.475
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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