Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HemE_1Methyltransferase, MtaA/CmuA family; KEGG: swo:Swol_0417 8.4e-64 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87. (382 aa)    
Predicted Functional Partners:
nqrF
2Fe-2S iron-sulfur cluster binding domain protein; KEGG: aha:AHA_1141 3.8e-10 nqrF; NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit K00345; COG: COG3894 Uncharacterized metal-binding protein; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.941
metH_1
B12 binding domain protein; KEGG: mbu:Mbur_1365 2.1e-44 corrinoid methyltransferase K00548; COG: COG5012 Predicted cobalamin binding protein; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.922
EDS06552.1
Hypothetical protein; KEGG: mmp:MMP0831 1.8e-22 mtbA; uroporphyrinogen decarboxylase (URO-D) K00599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
     0.917
metH_2
B12 binding domain protein; KEGG: mbu:Mbur_1365 1.8e-45 corrinoid methyltransferase K00548; COG: COG5012 Predicted cobalamin binding protein; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.909
yjiA
CobW/P47K family protein; KEGG: reh:H16_A3373 7.8e-18 putative GTPase (G3E family); COG: COG0523 Putative GTPases (G3E family); Psort location: Cytoplasmic, score: 8.87.
 
    0.835
hemE_2
Methyltransferase, MtaA/CmuA family; KEGG: mmp:MMP0831 8.5e-103 mtbA; uroporphyrinogen decarboxylase (URO-D) K00599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
   
0.810
hemE_3
Hypothetical protein; KEGG: mmp:MMP0831 4.3e-16 mtbA; uroporphyrinogen decarboxylase (URO-D) K00599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87.
 
    
0.755
hemZ
KEGG: cpe:CPE1935 9.2e-90 hemZ; probable coproporphyrinogen III oxidase K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.530
hemN_2
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.530
EDS05358.1
Hypothetical protein.
  
     0.519
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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