Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hndD_2Hydrogenase, Fe-only; KEGG: mta:Moth_1717 6.0e-134 iron hydrogenase, small subunit K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. (576 aa)    
Predicted Functional Partners:
sfrB_1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: cte:CT0282 6.4e-82 glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
 
 0.995
hndC_1
4Fe-4S binding domain protein; KEGG: tte:TTE0893 3.3e-243 nuoF; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.984
hndC_3
4Fe-4S binding domain protein; KEGG: swo:Swol_1701 3.0e-194 NADH dehydrogenase (quinone) K05903; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.982
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.957
hndC_2
4Fe-4S binding domain protein; KEGG: mth:MTH926 2.4e-13 tungsten formylmethanofuran dehydrogenase, subunit F homolog K00205; COG: COG1145 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.944
hndA
KEGG: tte:TTE0890 2.1e-42 nuoE; NADH:ubiquinone oxidoreductase 24 kD subunit K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score: 9.98.
 
 0.940
nuoE_2
Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: deh:cbdb_A683 4.4e-35 hymA; putative [Fe] hydrogenase, HymA subunit K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score: 9.98.
 
 0.937
EDS06174.1
4Fe-4S binding domain protein; KEGG: mma:MM1824 0.00011 formylmethanofuran dehydrogenase K00205; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.931
EDS06840.1
KEGG: afu:AF1203 1.4e-86 molybdopterin oxidoreductase, molybdopterin binding subunit K00183; COG: COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Psort location: Cytoplasmic, score: 8.87; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.926
HpdA
Radical SAM domain protein; KEGG: dsy:DSY0417 1.5e-34 pyruvate-formate lyase-activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.922
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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