Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sfrB_1Pyridine nucleotide-disulfide oxidoreductase; KEGG: cte:CT0282 6.4e-82 glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. (610 aa)    
Predicted Functional Partners:
hndD_2
Hydrogenase, Fe-only; KEGG: mta:Moth_1717 6.0e-134 iron hydrogenase, small subunit K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
 0.995
gltB_1
Class II glutamine amidotransferase; KEGG: gka:GK1431 0. glutamate synthaselarge subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
 
 0.989
hndC_3
4Fe-4S binding domain protein; KEGG: swo:Swol_1701 3.0e-194 NADH dehydrogenase (quinone) K05903; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
  
 0.976
HndD_1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 8.9e-195 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
 0.975
hndD_3
4Fe-4S binding domain protein; KEGG: chy:CHY_0733 7.8e-24 fdhA; NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-containing K00123; COG: COG3383 Uncharacterized anaerobic dehydrogenase; Psort location: CytoplasmicMembrane, score: 7.80.
 
 0.956
hndC_2
4Fe-4S binding domain protein; KEGG: mth:MTH926 2.4e-13 tungsten formylmethanofuran dehydrogenase, subunit F homolog K00205; COG: COG1145 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
  
 0.955
gltD_1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: tma:TM1217 1.5e-71 glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
  
 0.954
sfrB_2
Putative selenate reductase, YgfK subunit; KEGG: eci:UTI89_C3263 4.3e-195 ygfK; hypothetical protein YgfK K05299; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
  
 0.954
hndC_1
4Fe-4S binding domain protein; KEGG: tte:TTE0893 3.3e-243 nuoF; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.945
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.940
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.