Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YwaCRelA/SpoT domain protein; KEGG: bce:BC4341 3.4e-51 GTP pyrophosphokinase K00951; COG: COG2357 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (235 aa)    
Predicted Functional Partners:
relA
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.917
nrdD
KEGG: lla:L70400 2.3e-116 nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
nrdD-2
KEGG: tde:TDE1331 2.6e-220 nrdD; anaerobic ribonucleoside triphosphate reductase K00527; COG: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
EDS05089.1
Adenylate cyclase; KEGG: aeh:Mlg_1325 4.3e-12 adenylate cyclase K01768; COG: COG2954 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
folE
GTP cyclohydrolase I; KEGG: cpe:CPE1019 4.3e-60 mtrA; GTP cyclohydrolase K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score: 8.87.
     
  0.800
MoaA_1
Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.800
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.737
gidA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
   
    0.654
EDS06635.1
Hypothetical protein; COG: COG1284 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.533
btuR
Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: tte:TTE0370 2.2e-26 btuR; ATP:corrinoid adenosyltransferase K00798; COG: COG2109 ATP:corrinoid adenosyltransferase; Psort location: Cytoplasmic, score: 9.98.
       0.515
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.