Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spoVADStage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75. (334 aa)    
Predicted Functional Partners:
EDS06647.1
Putative stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.990
spoVAE
Stage V sporulation protein AE; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
 
  
 0.981
EDS06648.1
Hypothetical protein; COG: NOG11552 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.952
gpr
GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.922
SpoIIAA
KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.
 
   
 0.917
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.914
EDS06649.1
Hypothetical protein; COG: NOG11305 non supervised orthologous group.
 
    0.886
sigF
Putative RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.878
GerAA
Hypothetical protein; COG: NOG05963 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.866
spoVT
Stage V sporulation protein T; COG: COG2002 Regulators of stationary/sporulation gene expression; Psort location: Cytoplasmic, score: 9.98.
  
   
 0.825
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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