Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
spoIIABAnti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (151 aa)    
Predicted Functional Partners:
SpoIIAA
KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.
 
 
 0.998
sigF
Putative RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.955
EDS06647.1
Putative stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
   
 0.919
spoVAD
Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75.
 
  
 0.914
spoVAE
Stage V sporulation protein AE; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
 
     0.913
spoIIE
Putative stage II sporulation protein E; KEGG: tte:TTE2396 2.1e-58 rsbU; serine phosphatase RsbU, regulator of sigma subunit K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.907
spoIIGA
KEGG: gka:GK1126 7.3e-15 spoIIGA; protease (sporulation sigma-E factor processing peptidase); COG: NOG09744 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.891
EDS05611.1
Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.867
sigG
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.854
spoIIR
Stage II sporulation protein R; COG: NOG13215 non supervised orthologous group.
  
   
 0.850
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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