Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDS06670.1Macro domain protein; KEGG: reh:H16_A1552 3.1e-27 predicted phosphatase homolog to the C-terminal domain of histone macroH2A1; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87. (267 aa)    
Predicted Functional Partners:
EDS05183.1
Hypothetical protein; KEGG: hit:NTHI1634 1.7e-15 NAD-dependent deacetylase sirtuin 5 K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: Cytoplasmic, score: 8.87.
  0.913
EDS06671.1
Hypothetical protein; KEGG: reh:H16_A2653 1.6e-14 G:T/U mismatch-specific DNA glycosylase K01249; COG: COG3663 G:T/U mismatch-specific DNA glycosylase; Psort location: Cytoplasmic, score: 8.87.
       0.775
mutS_1
MutS domain V protein; KEGG: btk:BT9727_3510 1.2e-16 mutS; DNA mismatch repair protein K03555; COG: COG0249 Mismatch repair ATPase (MutS family); Psort location: CytoplasmicMembrane, score: 7.63.
   
   0.757
rplX
Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.697
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.694
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
   0.639
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.637
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
   0.575
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.565
cmk
Cytidylate kinase; KEGG: ljo:LJ1089 2.3e-52 cytidylate kinase K00945; COG: COG0283 Cytidylate kinase; Psort location: Cytoplasmic, score: 8.87.
 
      0.562
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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