Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDS06671.1Hypothetical protein; KEGG: reh:H16_A2653 1.6e-14 G:T/U mismatch-specific DNA glycosylase K01249; COG: COG3663 G:T/U mismatch-specific DNA glycosylase; Psort location: Cytoplasmic, score: 8.87. (166 aa)    
Predicted Functional Partners:
mutY
KEGG: sth:STH1727 1.1e-72 A/G-specific adenine glycosylase K03575; COG: COG1194 A/G-specific DNA glycosylase; Psort location: CytoplasmicMembrane, score: 7.80; Belongs to the SfsA family.
    
 0.799
EDS06670.1
Macro domain protein; KEGG: reh:H16_A1552 3.1e-27 predicted phosphatase homolog to the C-terminal domain of histone macroH2A1; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87.
       0.775
mutS_1
MutS domain V protein; KEGG: btk:BT9727_3510 1.2e-16 mutS; DNA mismatch repair protein K03555; COG: COG0249 Mismatch repair ATPase (MutS family); Psort location: CytoplasmicMembrane, score: 7.63.
     
 0.760
xth
Exodeoxyribonuclease III; KEGG: cac:CAC0222 4.4e-106 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score: 9.98.
    
 0.708
comC
Bacterial peptidase A24, N-terminal domain protein; KEGG: tte:TTE1266 3.5e-42 pppA; leader peptidase (prepilin peptidase) / N-methyltransferase K02654; COG: COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.515
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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