Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hydEIron-only hydrogenase maturation rSAM protein HydE; KEGG: bth:BT1835 4.2e-69 biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87. (229 aa)    
Predicted Functional Partners:
hydF
Hydrogenase maturation GTPase HydF; KEGG: hpa:HPAG1_1378 3.1e-13 putative thiophene/furan oxidation protein K00058; COG: COG1160 Predicted GTPases.
   
 0.992
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.952
hydG
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: cpr:CPR_2462 2.5e-17 radical SAM domain protein K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.945
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
  0.900
bioB_1
Radical SAM domain protein; KEGG: aae:aq_975 5.8e-09 bioB; biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
EDS05254.1
Putative iron-only hydrogenase system regulator; COG: NOG17852 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
    0.811
HndD_1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 8.9e-195 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.734
hndD_2
Hydrogenase, Fe-only; KEGG: mta:Moth_1717 6.0e-134 iron hydrogenase, small subunit K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.698
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
  
 0.671
EDS06718.1
Rubredoxin; KEGG: cpr:CPR_0938 1.8e-219 periplasmic [Fe] hydrogenase 1 K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.619
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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