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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (248 aa)    
Predicted Functional Partners:
EDS08554.1
Hypothetical protein; KEGG: tko:TK0067 3.5e-10 nicotinamide mononucleotide adenylyltransferase K00952; COG: COG1056 Nicotinamide mononucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.951
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.949
deoD
KEGG: bcl:ABC4021 1.3e-76 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
 0.923
pncA
Isochorismatase family protein; KEGG: pab:PAB1720 3.7e-15 nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score: 8.87.
  
 0.921
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.920
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.916
nudC
Hydrolase, NUDIX family; KEGG: lpl:lp_3123 2.0e-46 pyrophosphatase (putative) K03659; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Psort location: Cytoplasmic, score: 8.87.
    
 0.906
rihA
KEGG: cpf:CPF_2260 1.2e-50 nucleoside hydrolase, IunH family K01239; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.903
rihB
KEGG: efa:EF2587 2.6e-12 inosine-uridine preferring nucleoside hydrolase K01239; COG: COG1957 Inosine-uridine nucleoside N-ribohydrolase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.903
ycjU
HAD hydrolase, family IA, variant 3; KEGG: vfi:VFA0937 4.8e-29 phosphoglycolate phosphatase K01091; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
       0.681
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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