Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ycjUHAD hydrolase, family IA, variant 3; KEGG: vfi:VFA0937 4.8e-29 phosphoglycolate phosphatase K01091; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87. (217 aa)    
Predicted Functional Partners:
cobB-2
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.679
treP
Glycosyl hydrolase family 65 central catalytic domain protein; KEGG: nca:Noca_3421 5.8e-136 kojibiose phosphorylase; COG: COG1554 Trehalose and maltose hydrolases (possible phosphorylases); Psort location: Cytoplasmic, score: 8.87.
 
  
 0.596
zitR
Transcriptional regulator, MarR family; COG: COG1846 Transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
       0.580
EDS06810.1
Glycosyl hydrolase family 65 central catalytic domain protein; KEGG: ava:Ava_3752 1.9e-98 HAD-superfamily hydrolase subfamily IA, variant 3 K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.568
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
     
 0.563
EDS06682.1
KEGG: hpa:HPAG1_0758 4.6e-56 hypothetical protein K00459; COG: COG2070 Dioxygenases related to 2-nitropropane dioxygenase; Psort location: Cytoplasmic, score: 8.87.
       0.479
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
     
 0.470
accC
acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
       0.462
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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