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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdaAAKEGG: ljo:LJ1328 9.2e-58 L-serine dehydratase alpha subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family. (284 aa)    
Predicted Functional Partners:
sdaAB
KEGG: btk:BT9727_3885 1.7e-51 sdhB; L-serine dehydratase, beta subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
 0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.956
ilvA
KEGG: fnu:FN1411 6.2e-116 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase.
  
 
 0.923
dsdA
KEGG: fnu:FN0553 3.3e-140 D-serine dehydratase K01753; COG: COG3048 D-serine dehydratase; Psort location: Cytoplasmic, score: 8.87; Belongs to the serine/threonine dehydratase family. DsdA subfamily.
     
 0.914
cysE
KEGG: gka:GK0084 1.1e-63 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98.
     
 0.912
EDS07204.1
CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-30 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 9.97.
  
  
  0.911
hom_2
KEGG: chy:CHY_1912 6.1e-125 hom; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.822
hom_1
KEGG: tte:TTE2620 5.9e-79 thrA2; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.822
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.815
GloA
Glyoxalase family protein; KEGG: fnu:FN0356 3.8e-36 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.803
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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