EDS06722.1 protein (Clostridium scindens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EDS06722.1

Hypothetical protein; Psort location: Extracellular, score: 8.82. (64 aa)

Predicted Functional Partners:

RlmL

0.495

rdgB

0.450

EDS06719.1

0.423

Your Current Organism:

Clostridium scindens

NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDS06719.1	EDS06722.1	CLOSCI_02342	CLOSCI_02345	KEGG: spd:SPD_1659 1.2e-14 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.	Hypothetical protein; Psort location: Extracellular, score: 8.82.	0.423
EDS06719.1	RlmL	CLOSCI_02342	CLOSCI_02344	KEGG: spd:SPD_1659 1.2e-14 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.	Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.	0.735
EDS06719.1	rdgB	CLOSCI_02342	CLOSCI_02343	KEGG: spd:SPD_1659 1.2e-14 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.	Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.971
EDS06722.1	EDS06719.1	CLOSCI_02345	CLOSCI_02342	Hypothetical protein; Psort location: Extracellular, score: 8.82.	KEGG: spd:SPD_1659 1.2e-14 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.	0.423
EDS06722.1	RlmL	CLOSCI_02345	CLOSCI_02344	Hypothetical protein; Psort location: Extracellular, score: 8.82.	Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.	0.495
EDS06722.1	rdgB	CLOSCI_02345	CLOSCI_02343	Hypothetical protein; Psort location: Extracellular, score: 8.82.	Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.450
RlmL	EDS06719.1	CLOSCI_02344	CLOSCI_02342	Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.	KEGG: spd:SPD_1659 1.2e-14 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.	0.735
RlmL	EDS06722.1	CLOSCI_02344	CLOSCI_02345	Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.	Hypothetical protein; Psort location: Extracellular, score: 8.82.	0.495
RlmL	rdgB	CLOSCI_02344	CLOSCI_02343	Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.	Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.771
rdgB	EDS06719.1	CLOSCI_02343	CLOSCI_02342	Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	KEGG: spd:SPD_1659 1.2e-14 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.	0.971
rdgB	EDS06722.1	CLOSCI_02343	CLOSCI_02345	Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Hypothetical protein; Psort location: Extracellular, score: 8.82.	0.450
rdgB	RlmL	CLOSCI_02343	CLOSCI_02344	Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Hypothetical protein; KEGG: bcz:BCZK1441 1.3e-104 methyltransferase K00599; COG: COG0116 Predicted N6-adenine-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.	0.771