| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS08104.1 | sigE | CLOSCI_00415 | CLOSCI_01117 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.772 |
| EDS08104.1 | sigG | CLOSCI_00415 | CLOSCI_01121 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.776 |
| EDS08104.1 | sigK | CLOSCI_00415 | CLOSCI_00041 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.768 |
| EDS08104.1 | spo0A_4 | CLOSCI_00415 | CLOSCI_02419 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver. | 0.777 |
| EDS08104.1 | spoIIAB | CLOSCI_00415 | CLOSCI_02267 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.785 |
| EDS08104.1 | spoIIID | CLOSCI_00415 | CLOSCI_03108 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Sporulation transcriptional regulator SpoIIID; COG: NOG13855 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.854 |
| EDS08104.1 | spoIIR | CLOSCI_00415 | CLOSCI_03123 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Stage II sporulation protein R; COG: NOG13215 non supervised orthologous group. | 0.828 |
| EDS08104.1 | spoIVA | CLOSCI_00415 | CLOSCI_00690 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Stage IV sporulation protein A; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.875 |
| EDS08104.1 | spoVAD | CLOSCI_00415 | CLOSCI_02261 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75. | 0.795 |
| EDS08104.1 | spoVT | CLOSCI_00415 | CLOSCI_01130 | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Stage V sporulation protein T; COG: COG2002 Regulators of stationary/sporulation gene expression; Psort location: Cytoplasmic, score: 9.98. | 0.823 |
| sigE | EDS08104.1 | CLOSCI_01117 | CLOSCI_00415 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.772 |
| sigE | sigG | CLOSCI_01117 | CLOSCI_01121 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.416 |
| sigE | spo0A_4 | CLOSCI_01117 | CLOSCI_02419 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver. | 0.796 |
| sigE | spoIIAB | CLOSCI_01117 | CLOSCI_02267 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.786 |
| sigE | spoIIID | CLOSCI_01117 | CLOSCI_03108 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation transcriptional regulator SpoIIID; COG: NOG13855 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.803 |
| sigE | spoIIR | CLOSCI_01117 | CLOSCI_03123 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein R; COG: NOG13215 non supervised orthologous group. | 0.770 |
| sigE | spoIVA | CLOSCI_01117 | CLOSCI_00690 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein A; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.784 |
| sigE | spoVAD | CLOSCI_01117 | CLOSCI_02261 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75. | 0.774 |
| sigE | spoVT | CLOSCI_01117 | CLOSCI_01130 | RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein T; COG: COG2002 Regulators of stationary/sporulation gene expression; Psort location: Cytoplasmic, score: 9.98. | 0.805 |
| sigG | EDS08104.1 | CLOSCI_01121 | CLOSCI_00415 | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.776 |