Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS06380.1DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (675 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.958
EDS07735.1
DEAD2 domain protein; KEGG: mja:MJ0942 7.3e-20 dinG; ATP-dependent DNA helicase DinG, putative K01529; COG: COG1199 Rad3-related DNA helicases; Psort location: Cytoplasmic, score: 8.87.
   
 0.952
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.951
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.948
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 0.939
EDS08494.1
Helicase C-terminal domain protein; KEGG: mbo:Mb2127 1.1e-13 helZ; probable helicase HelZ; COG: COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.827
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.823
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.811
EDS08675.1
KEGG: lwe:lwe1660 7.9e-21 DNA/RNA helicase protein K01529; COG: COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Psort location: Cytoplasmic, score: 8.87.
   
 0.801
EDS07977.1
Hypothetical protein; KEGG: rno:309804 1.6e-08 Cdc2l6_predicted; cell division cycle 2-like 6 (CDK8-like) (predicted) K02208; COG: KOG3544 Collagens (type IV and type XIII), and related proteins; Psort location: Cytoplasmic, score: 8.87.
   
 0.705
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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