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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lapBTetratricopeptide repeat protein; KEGG: eci:UTI89_C2868 1.1e-210 yphG; hypothetical protein YphG K00754; COG: NOG06209 non supervised orthologous group. (1090 aa)    
Predicted Functional Partners:
araC_2
KEGG: bcz:BCZK3497 2.2e-10 adaA; transcriptional regulator, AraC family K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98.
 
    0.880
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.567
EDS08433.1
Dinuclear metal center protein, YbgI family; COG: COG0327 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
  
    0.559
EDS05413.1
Hypothetical protein; KEGG: cal:orf19.335 0.0016 poorly conserved hypothetical protein K01768; COG: COG3291 FOG: PKD repeat.
 
 
 
 0.507
WcaJ
KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.439
EDS07617.1
DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.430
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
       0.426
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.422
nnr
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
       0.422
recJ
KEGG: cac:CAC2232 4.3e-147 recJ; SsDNA exonuclease, RecJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.87.
     
 0.422
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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