Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HpdARadical SAM domain protein; KEGG: dsy:DSY0417 1.5e-34 pyruvate-formate lyase-activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98. (288 aa)    
Predicted Functional Partners:
cutC_2
Pyruvate formate lyase; KEGG: cno:NT01CX_0385 3.9e-59 pyruvate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.968
hndD_2
Hydrogenase, Fe-only; KEGG: mta:Moth_1717 6.0e-134 iron hydrogenase, small subunit K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.922
HndD_1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 8.9e-195 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.922
cutC_1
Putative formate C-acetyltransferase; KEGG: gsu:GSU2101 4.5e-239 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.888
pflB-2
KEGG: cya:CYA_0477 9.2e-264 pflB; formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.882
pflB
KEGG: bce:BC0491 6.8e-268 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.880
AdhE
Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.829
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.784
xylB-2
Xylulokinase; KEGG: rxy:Rxyl_0402 5.3e-94 xylulokinase K00854; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: Cytoplasmic, score: 8.87.
       0.773
urdA
FAD binding domain protein; KEGG: ctc:CTC01488 1.6e-55 fumarate reductase flavoprotein subunit K00244; COG: COG3976 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.49.
  
 
 0.711
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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