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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KbaYKetose-bisphosphate aldolase; KEGG: chy:CHY_0128 3.8e-68 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87. (275 aa)    
Predicted Functional Partners:
pfkB
1-phosphofructokinase; KEGG: cac:CAC2951 1.0e-58 lacC; tagatose-6-phosphate kinase K00917; COG: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Psort location: Cytoplasmic, score: 8.87; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.983
pfkA-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 
 0.925
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.925
pfp_1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.924
pfp_2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.924
EDS07489.1
Hypothetical protein; KEGG: ath:At1g18270 1.7e-84 T10O22.24; ketose-bisphosphate aldolase class-II family protein K00120; COG: KOG4153 Fructose 1,6-bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
      0.892
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; KEGG: ppr:PBPRA1276 3.3e-53 putative 2-keto-3-deoxy-6-phosphogluconatealdolase K01625:K01650; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score: 9.65.
    
 0.821
ydhV_1
Aldehyde ferredoxin oxidoreductase, tungsten cofactor-binding domain protein; KEGG: pfu:PF0346 1.4e-102 aldehyde:ferredoxin oxidoreductase (aor) K03738; COG: COG2414 Aldehyde:ferredoxin oxidoreductase.
     
  0.800
ydhV_2
Aldehyde ferredoxin oxidoreductase, tungsten cofactor-binding domain protein; KEGG: swo:Swol_1703 1.2e-199 aldehyde ferredoxin oxidoreductase K03738; COG: COG2414 Aldehyde:ferredoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.87.
     
  0.800
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.784
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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