Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfkB1-phosphofructokinase; KEGG: cac:CAC2951 1.0e-58 lacC; tagatose-6-phosphate kinase K00917; COG: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Psort location: Cytoplasmic, score: 8.87; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa)    
Predicted Functional Partners:
FruA
KEGG: cpr:CPR_0550 3.4e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.998
KbaY
Ketose-bisphosphate aldolase; KEGG: chy:CHY_0128 3.8e-68 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.982
glpR_1
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.880
gatD
GroES-like protein; KEGG: lin:lin0506 1.3e-65 similar to polyol (sorbitol) dehydrogenase K00008; COG: KOG0024 Sorbitol dehydrogenase; Psort location: Cytoplasmic, score: 9.65.
 
    0.819
xylB-4
Putative xylulokinase; KEGG: cac:CAC2612 6.8e-94 xylB; xylulose kinase K00854; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: Cytoplasmic, score: 8.87.
     
 0.764
SrlR_1
Transcriptional regulator, DeoR family; KEGG: net:Neut_1829 0.00052 ribose 5-phosphate isomerase K01806; COG: COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.719
glcR
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.703
pfoR
Perfringolysin O regulator protein; KEGG: mta:Moth_0013 2.0e-07 PTS fructose IIC component K02769:K02770; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.699
srlR_2
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.671
lacR
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.660
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (20%) [HD]