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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CrhPhosphocarrier, HPr family; KEGG: btl:BALH_4643 1.6e-12 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 9.98. (85 aa)    
Predicted Functional Partners:
ptsP
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.908
ptsP-2
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.898
ptsI_1
PEP-utilizing enzyme, TIM barrel domain protein; KEGG: blo:BL0411 6.4e-46 ptsI; phosphoenolpyruvate-protein phosphotransferase K02766; COG: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); Psort location: Cytoplasmic, score: 9.98; Belongs to the PEP-utilizing enzyme family.
 
 
 0.885
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
 
 
 
 0.885
FruA
KEGG: cpr:CPR_0550 3.4e-163 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.858
yvcJ
Hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.822
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
     
 0.810
EDS06425.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.783
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.783
dagK
Lipid kinase, YegS/Rv2252/BmrU family; KEGG: eci:UTI89_C2362 4.3e-21 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; Psort location: Cytoplasmic, score: 8.87.
       0.606
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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