close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menGMethyltransferase domain protein; KEGG: sru:SRU_1592 2.7e-19 menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (202 aa)    
Predicted Functional Partners:
mtrR_2
Transcriptional regulator, TetR family; KEGG: bha:BH3415 0.00026 NADH dehydrogenase K03885; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.838
mepA_1
MATE efflux family protein; COG: COG0534 Na+-driven multidrug efflux pump; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.641
EDS06224.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.572
EDS06243.1
Restriction endonuclease; COG: NOG37482 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.478
EDS06222.1
DNA-binding helix-turn-helix protein; KEGG: eba:ebA2762 1.7e-05 boxR; putative regulator of aerobic benzoate metabolic operon containing shikimate kinase-like domain K00891; COG: NOG37851 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.419
pdxB-3
KEGG: hwa:HQ2066A 2.6e-60 serA; phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.414
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.