Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mepA_1MATE efflux family protein; COG: COG0534 Na+-driven multidrug efflux pump; Psort location: CytoplasmicMembrane, score: 9.99. (442 aa)    
Predicted Functional Partners:
EDS06227.1
Hypothetical protein; COG: COG1321 Mn-dependent transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
  
    0.700
mtrR_2
Transcriptional regulator, TetR family; KEGG: bha:BH3415 0.00026 NADH dehydrogenase K03885; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
     0.652
menG
Methyltransferase domain protein; KEGG: sru:SRU_1592 2.7e-19 menaquinone biosynthesis methyltransferase UbiE K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87.
 
     0.640
EDS06243.1
Restriction endonuclease; COG: NOG37482 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.465
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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