Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lepB-5KEGG: sth:STH1472 3.8e-20 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Belongs to the peptidase S26 family. (185 aa)    
Predicted Functional Partners:
DacB_1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: tte:TTE0925 9.7e-47 dacC; D-alanyl-D-alanine carboxypeptidase K01286; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
       0.725
EDS06271.1
Hypothetical protein.
       0.554
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.553
EDS06267.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.552
Gmr
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VFA0796 2.2e-06 sensor protein; COG: COG2199 FOG: GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
       0.552
minE
Putative cell division topological specificity factor MinE; Psort location: Cytoplasmic, score: 8.87.
   
    0.550
gspF
Bacterial type II secretion system domain protein F; COG: COG1459 Type II secretory pathway, component PulF; Psort location: CytoplasmicMembrane, score: 9.97.
 
     0.539
EDS06266.1
Hypothetical protein; COG: COG1305 Transglutaminase-like enzymes, putative cysteine proteases.
  
    0.512
rseP
RIP metalloprotease RseP; KEGG: cac:CAC1796 2.5e-64 predicted membrane-associated Zn-dependent protease; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1; Psort location: CytoplasmicMembrane, score: 7.63.
 
  
 0.458
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.443
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.