Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lytB_2SpoIID/LytB domain protein; COG: COG2385 Sporulation protein and related proteins. (294 aa)    
Predicted Functional Partners:
spoIVA
Stage IV sporulation protein A; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.895
spoIIE
Putative stage II sporulation protein E; KEGG: tte:TTE2396 2.1e-58 rsbU; serine phosphatase RsbU, regulator of sigma subunit K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.823
SpoIIAA
KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.
  
   
 0.762
yabP
Sporulation protein YabP; COG: NOG13819 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.745
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.742
EDS08104.1
Stage III sporulation protein AA; COG: COG3854 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.732
spoIIQ
KEGG: cya:CYA_2269 7.0e-05 peptidase, M23B family; COG: COG0739 Membrane proteins related to metalloendopeptidases.
 
   
 0.726
spoIVB
SpoIVB peptidase; KEGG: btl:BALH_3781 9.1e-51 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.
  
     0.725
spoIIR
Stage II sporulation protein R; COG: NOG13215 non supervised orthologous group.
  
   
 0.721
spoVAD
Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75.
  
   
 0.719
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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