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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ywlCSua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (352 aa)    
Predicted Functional Partners:
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
  
 0.902
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.817
cwlD
KEGG: bce:BC0167 2.4e-34 spore-specific N-acetylmuramoyl-L-alanine amidase K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase.
       0.816
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.747
TadA_2
KEGG: cpf:CPF_1322 9.1e-51 cytidine/deoxycytidylate deaminase family protein K01493; COG: COG2131 Deoxycytidylate deaminase; Psort location: Cytoplasmic, score: 8.87.
       0.704
YdhD
SH3 domain protein; KEGG: ctc:CTC01180 6.5e-21 spore peptidoglycan hydrolase (N-acetylglucosaminidase) K06306; COG: COG3858 Predicted glycosyl hydrolase.
       0.613
EDS06289.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.553
sbcC
KEGG: ctc:CTC00579 8.6e-110 sbcC; exonuclease sbcC K03546; COG: COG0419 ATPase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87.
   
   0.498
EDS06288.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.453
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
  
 0.425
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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