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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnNMTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa)    
Predicted Functional Partners:
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.985
mtnK
S-methyl-5-thioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
  
  
 0.934
dcm-2
KEGG: cac:CAC1222 4.8e-100 DNA-methyltransferase (cytosine-specific) K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.
    
  0.901
hpaIIM
Modification methylase HpaII; KEGG: mpe:MYPE9800 3.9e-75 cytosine-specific DNA methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.
    
  0.901
EDS08195.1
Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
      0.682
pgi
KEGG: bcl:ABC2906 1.4e-164 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
 
   
 0.612
EDS06314.1
Conserved hypothetical protein TIGR03905; COG: NOG17478 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.588
lsrB
Sugar-binding domain protein; KEGG: msm:MSMEG_3095 1.8e-10 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component.
      
 0.538
EDS06316.1
Hypothetical protein; KEGG: bba:Bd1032 0.0026 mepA; hypothetical protein K07261; Psort location: CytoplasmicMembrane, score: 7.63.
       0.533
metG-2
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.521
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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