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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaX_1Putative DNA polymerase III, subunit gamma and tau; KEGG: tte:TTE0097 3.4e-51 holB; ATPase involved in DNA replication K02341; COG: COG2812 DNA polymerase III, gamma/tau subunits; Psort location: Cytoplasmic, score: 8.87. (329 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.990
dnaE
KEGG: tte:TTE1818 0. dnaE; DNA polymerase III alpha subunit K02337; COG: COG0587 DNA polymerase III, alpha subunit; Psort location: Cytoplasmic, score: 9.98.
 
 0.988
holA
DNA polymerase III, delta subunit; KEGG: bld:BLi02748 6.3e-43 yqeN; similar to proteins; RBL00675 K02340; COG: COG1466 DNA polymerase III, delta subunit.
 
 
 0.987
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
0.931
polC
DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.920
gmk_1
Hypothetical protein; KEGG: tws:TW406 1.8e-09 gmk; guanylate kinase K00942; COG: COG0194 Guanylate kinase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.900
EDS06321.1
PSP1 C-terminal domain protein; COG: COG1774 Uncharacterized homolog of PSP1; Psort location: Cytoplasmic, score: 8.87.
  
   0.858
speA
Orn/Lys/Arg decarboxylase, major domain protein; KEGG: tte:TTE0093 2.5e-71 ldcC; Arginine/lysine/ornithine decarboxylases K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases; Psort location: Cytoplasmic, score: 8.87.
       0.843
yfiC
Methyltransferase domain protein; KEGG: ctc:CTC00225 2.9e-54 methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87.
       0.843
pgi
KEGG: bcl:ABC2906 1.4e-164 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
   
 
 0.824
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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