Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PucR_2Hypothetical protein; KEGG: shn:Shewana3_2682 0.00082 transcriptional regulator, CdaR K01694; COG: COG3835 Sugar diacid utilization regulator; Psort location: Cytoplasmic, score: 8.87. (355 aa)    
Predicted Functional Partners:
DmdA_2
Aconitase domain protein; KEGG: ecp:ECP_0784 2.8e-239 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 9.98.
 
     0.829
EDS08709.1
Hypothetical protein; KEGG: btl:BALH_3665 0.00019 ptsH; phosphocarrier protein HPr K00889; Psort location: Cytoplasmic, score: 8.87.
  
     0.743
EDS05745.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
  
     0.583
mecB
COG: COG4862 Negative regulator of genetic competence, sporulation and motility; Psort location: Cytoplasmic, score: 8.87.
  
     0.566
EDS07942.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.558
EDS06325.1
Hypothetical protein.
       0.525
EDS08339.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.522
secG
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.472
sigM_2
Sigma-70 region 2; KEGG: btl:BALH_3229 2.0e-14 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
       0.470
EDS04936.1
Hypothetical protein.
  
     0.443
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (12%) [HD]