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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cph2Diguanylate cyclase (GGDEF) domain protein; KEGG: shn:Shewana3_3829 1.9e-35 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: Cytoplasmic, score: 8.87. (584 aa)    
Predicted Functional Partners:
adrA
Diguanylate cyclase (GGDEF) domain protein; KEGG: shn:Shewana3_3829 1.9e-24 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
 0.985
ycdT
Diguanylate cyclase (GGDEF) domain protein; KEGG: eci:UTI89_C2343 2.6e-18 yegE; putative sensor-type protein; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
 0.960
EDS05417.1
Hypothetical protein; KEGG: shn:Shewana3_3829 0.0029 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.884
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 0.853
EDS07477.1
HD domain protein; KEGG: ava:Ava_1777 4.6e-26 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.830
Gmr
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VFA0796 2.2e-06 sensor protein; COG: COG2199 FOG: GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.825
YeaI
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 4.3e-07 sensory transduction protein kinase; COG: COG2199 FOG: GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.815
EDS05027.1
Stage II sporulation protein E; KEGG: mta:Moth_0103 3.8e-08 serine phosphatase K06382; COG: NOG28446 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.732
EDS06726.1
Hypothetical protein; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.697
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.669
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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