Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hypA_1Hydrogenase expression/synthesis hypA family; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (117 aa)    
Predicted Functional Partners:
EDS06174.1
4Fe-4S binding domain protein; KEGG: mma:MM1824 0.00011 formylmethanofuran dehydrogenase K00205; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.945
hypB
Hydrogenase accessory protein HypB; KEGG: tte:TTE2387 0.00013 argK; putative periplasmic protein kinase ArgK and related GTPases of G3E family K07588; COG: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.917
gltD_1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: tma:TM1217 1.5e-71 glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.790
surE
KEGG: mth:MTH1435 4.0e-34 surE; acid phosphatase K03787; COG: COG0496 Predicted acid phosphatase; Psort location: Cytoplasmic, score: 8.87.
       0.761
lsrK
Carbohydrate kinase, FGGY family protein; KEGG: abo:ABO_1407 2.8e-56 sugar kinase, putative K00924; COG: COG1070 Sugar (pentulose and hexulose) kinases; Psort location: Cytoplasmic, score: 8.87.
       0.746
EDS08070.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.707
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.631
EDS06169.1
Hypothetical protein; COG: COG1578 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.621
EDS06170.1
Hypothetical protein.
       0.621
KduD_2
Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: ecs:ECs3630 1.5e-89 putative oxidoreductase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98.
       0.621
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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