Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SigW_2Sigma-70 region 2; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)    
Predicted Functional Partners:
EDS06180.1
Hypothetical protein; COG: COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; Psort location: CytoplasmicMembrane, score: 9.97.
 
     0.880
yxlF_2
KEGG: noc:Noc_2142 1.1e-40 ABC transporter, ATPase subunit; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
    0.864
EDS06178.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
   
 0.854
sigM_1
Sigma-70 region 2; KEGG: shn:Shewana3_0763 5.0e-11 RNA polymerase, sigma-24 subunit, ECF subfamily K00058; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.646
sigM_2
Sigma-70 region 2; KEGG: btl:BALH_3229 2.0e-14 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
  
     0.625
EDS06176.1
Transcriptional regulator, TetR family; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
       0.565
SigR
Sigma-70 region 2; KEGG: bcz:BCZK3297 3.7e-15 RNA polymerase ECF-type sigma factor K03088; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.550
EDS06181.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.422
yxlF_1
ABC transporter, ATP-binding protein; KEGG: rru:Rru_A3130 1.3e-42 ABC transporter component K06020; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
    0.408
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.