Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
cckAATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (549 aa)    
Predicted Functional Partners:
ycdT
Diguanylate cyclase (GGDEF) domain protein; KEGG: eci:UTI89_C2343 2.6e-18 yegE; putative sensor-type protein; COG: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.946
adrA
Diguanylate cyclase (GGDEF) domain protein; KEGG: shn:Shewana3_3829 1.9e-24 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.946
EDS05823.1
Hypothetical protein; COG: NOG17272 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.939
walR_2
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 6.2e-36 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65.
 
 
 0.920
EDS05417.1
Hypothetical protein; KEGG: shn:Shewana3_3829 0.0029 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.849
rcsC
Hypothetical protein; KEGG: psp:PSPPH_0770 5.9e-06 response regulator/sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase.
   
 
 0.840
cseB
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.3e-37 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.834
rbsB_3
Sugar-binding domain protein; KEGG: msm:MSMEG_3095 6.5e-25 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component.
   
 
 0.817
rbsB_1
Sugar-binding domain protein; KEGG: msm:MSMEG_3095 2.1e-15 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component.
   
 
 0.817
mglB_1
Hypothetical protein; KEGG: msm:MSMEG_3095 5.0e-12 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component.
   
 
 0.817
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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