Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS06081.1COG: COG1305 Transglutaminase-like enzymes, putative cysteine proteases. (375 aa)    
Predicted Functional Partners:
tlpA_2
Redoxin family protein; KEGG: mbo:Mb3945 2.4e-06 trxC; thioredoxin TrxC (TRX) (MPT46) K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins.
       0.530
YccM_3
4Fe-4S binding domain protein; KEGG: eci:UTI89_C1055 3.9e-17 yccM; putative electron transport protein YccM K00168; COG: COG0348 Polyferredoxin; Psort location: CytoplasmicMembrane, score: 9.97.
  
    0.494
zraS_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecp:ECP_4216 4.8e-30 sensor protein ZraS K07709; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.491
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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