Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
zraS_2ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecp:ECP_4216 4.8e-30 sensor protein ZraS K07709; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. (585 aa)    
Predicted Functional Partners:
sphR_2
Response regulator receiver domain protein; KEGG: ava:Ava_3369 5.6e-35 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.885
cseB
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.3e-37 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.802
walR_2
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 6.2e-36 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65.
  
   0.793
YccM_3
4Fe-4S binding domain protein; KEGG: eci:UTI89_C1055 3.9e-17 yccM; putative electron transport protein YccM K00168; COG: COG0348 Polyferredoxin; Psort location: CytoplasmicMembrane, score: 9.97.
       0.773
tlpA_2
Redoxin family protein; KEGG: mbo:Mb3945 2.4e-06 trxC; thioredoxin TrxC (TRX) (MPT46) K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.770
walR_10
Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.3e-42 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.765
srrA_3
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.3e-43 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.761
phoR_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.744
phoP_4
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.723
phoP_3
Response regulator receiver domain protein; KEGG: ava:Ava_3369 6.5e-41 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.710
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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