Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
natR_1LytTr DNA-binding domain protein; KEGG: rru:Rru_A0376 8.7e-07 transcriptional regulator, LytR/AlgR family K07705; COG: COG3279 Response regulator of the LytR/AlgR family; Psort location: Cytoplasmic, score: 8.87. (235 aa)    
Predicted Functional Partners:
ypdA_3
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE2344 7.8e-45 lytS2; predicted ATPase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.786
yehU_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bld:BLi00440 1.4e-40 putative ABC transporter (permease); RBL00398 K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.780
ypdA_4
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bld:BLi01366 5.0e-43 yesM; similar to two-component sensor histidine kinase [YesN]; RBL02409 K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.770
lytR_1
LytTr DNA-binding domain protein; KEGG: rru:Rru_A0376 0.00013 transcriptional regulator, LytR/AlgR family K07705; COG: COG3279 Response regulator of the LytR/AlgR family; Psort location: Cytoplasmic, score: 8.87.
  
     0.759
ypdA_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE2344 2.0e-46 lytS2; predicted ATPase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.735
ypdA_1
HAMP domain protein; KEGG: bld:BLi01366 3.7e-70 yesM; similar to two-component sensor histidine kinase [YesN]; RBL02409 K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
  
 0.725
EDS05668.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE0562 1.2e-14 baeS2; sensory transduction histidine kinases K07706; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.555
yehU_2
HAMP domain protein; KEGG: bha:BH3447 4.8e-61 two-component sensor histidine kinase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
  
 0.543
EDS05875.1
COG: COG4805 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.535
EDS06027.1
Hypothetical protein; KEGG: ssp:SSP0840 1.1e-13 accessory gene regulator C K07706; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.507
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (22%) [HD]