Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PrpC2KEGG: lla:L67186 6.4e-137 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98. (459 aa)    
Predicted Functional Partners:
DmdA_2
Aconitase domain protein; KEGG: ecp:ECP_0784 2.8e-239 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 9.98.
 
 0.992
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 0.964
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.949
EDS07091.1
Malic enzyme, NAD binding domain protein; KEGG: tte:TTE2332 9.9e-125 sfcA; malic enzyme K00027; COG: COG0281 Malic enzyme; Psort location: CytoplasmicMembrane, score: 9.97.
  
 
 0.948
betB
Aldehyde dehydrogenase (NAD) family protein; KEGG: tde:TDE0080 1.3e-175 gbsA; betaine aldehyde dehydrogenase K00130; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
  
 0.948
icd
Isocitrate dehydrogenase, NADP-dependent; KEGG: tte:TTE0387 4.1e-158 icd; Isocitrate dehydrogenases K00031; COG: COG0538 Isocitrate dehydrogenases; Psort location: Cytoplasmic, score: 8.87; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
 
 0.946
pta
Phosphate acetyltransferase; KEGG: hhe:HH1309 1.1e-100 pta; phosphotransacetylase K00625; COG: COG0280 Phosphotransacetylase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.928
EDS04956.1
Hypothetical protein; KEGG: lac:LBA0466 8.7e-133 phosphoenolpyruvate carboxykinase (ATP) K01610; COG: COG1866 Phosphoenolpyruvate carboxykinase (ATP).
  
 
 0.921
EDS08311.1
HMGL-like protein; KEGG: tte:TTE0472 2.0e-30 leuA2; homocitrate synthase K01655:K02594; COG: COG0119 Isopropylmalate/homocitrate/citramalate synthases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.919
pflB
KEGG: bce:BC0491 6.8e-268 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
     
 0.905
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.